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Related Concept Videos

Flexural Stress01:16

Flexural Stress

When analyzing bending in symmetric members, it's crucial to understand how stresses distribute when subjected to bending moments. This stress distribution is effectively described by applying fundamental mechanics and material science principles, particularly Hooke's Law for elastic materials.
Hooke's Law states that within the material's elastic limits, stress is directly proportional to strain. In a member experiencing a bending moment, the strain at any point is relative to its distance...
Base Excision Repair01:54

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
Base Excision Repair01:54

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Fibril-associated Collagen01:11

Fibril-associated Collagen

Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...

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Related Experiment Video

Updated: Jul 4, 2026

FLEX: Flight Exercise Training Protocol for the Fruit Fly Drosophila
03:47

FLEX: Flight Exercise Training Protocol for the Fruit Fly Drosophila

Published on: October 14, 2025

Abe Flexner, where are you? We need you!

Ronald A Arky

    Transactions of the American Clinical and Climatological Association
    |June 6, 2008
    PubMed
    Summary

    A century ago, the Flexner Report transformed medical education. Today, despite scientific advances, medical training remains stagnant, necessitating urgent reform for 21st-century healthcare.

    Area of Science:

    • Medical Education
    • History of Medicine
    • Healthcare Systems

    Background:

    • The 1910 Flexner Report revolutionized medical education in the U.S. and Canada, establishing university-based, research-integrated medical schools.
    • This reform led to North American institutions becoming global leaders in medical training and practice for much of the 20th century.

    Discussion:

    • Despite significant advancements in medical science and clinical environments over the past 50 years, medical education curricula and training processes have seen minimal change.
    • Medical education is not yet fully recognized as a science, evidenced by a lack of continuity across undergraduate, postgraduate, and continuing education stages.

    Key Insights:

    • Medical education currently functions as an 'orphan' discipline, reliant on clinical practice and research funding, with educators facing similar academic marginalization.

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    Flexural Rigidity Measurements of Biopolymers Using Gliding Assays
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    Related Experiment Videos

    Last Updated: Jul 4, 2026

    FLEX: Flight Exercise Training Protocol for the Fruit Fly Drosophila
    03:47

    FLEX: Flight Exercise Training Protocol for the Fruit Fly Drosophila

    Published on: October 14, 2025

    Open-source Toolkit: Benchtop Carbon Fiber Microelectrode Array for Nerve Recording
    07:50

    Open-source Toolkit: Benchtop Carbon Fiber Microelectrode Array for Nerve Recording

    Published on: October 29, 2021

    Flexural Rigidity Measurements of Biopolymers Using Gliding Assays
    07:55

    Flexural Rigidity Measurements of Biopolymers Using Gliding Assays

    Published on: November 9, 2012

  • The current state of medical education lags behind the rapid evolution of science and medicine, failing to adapt to modern healthcare demands.
  • Outlook:

    • There is a critical need for a contemporary figure, akin to Abraham Flexner, to spearhead a revitalization of medical education.
    • Streamlining medical education for the 21st century requires addressing systemic inertia and complacency to integrate advancements and improve training continuity.