A non-invasive, relocatable stereotactic frame for fractionated radiotherapy and multiple imaging

Area of Science:

• Medical Physics
• Radiotherapy Technology
• Neurosurgery

Background:

• Fractionated stereotactic external beam radiotherapy (SRT) requires precise patient immobilization and target localization.
• Existing methods may have limitations in accuracy, comfort, or adaptability for various imaging modalities.

Purpose of the Study:

• To develop and evaluate a novel non-invasive, relocatable stereotactic frame for fractionated SRT.
• To assess the accuracy of target localization and patient repositioning using the new immobilization device.

Main Methods:

• Development of a stereotactic frame with fixation via the upper dentition.
• Testing of the frame's repositioning accuracy using antero-posterior and lateral displacement measurements.
• Evaluation of the frame's capability for 3D target localization with CT, MRI, PET, and cerebral angiography.
• Assessment of precise isocentric positioning for radiotherapy delivery.

Main Results:

• The developed frame is non-invasive and relocatable.
• Repositioning tests demonstrated mean antero-posterior and lateral displacements of 1.0 mm.
• The frame facilitates accurate 3D target localization across multiple imaging modalities.
• Precise isocentric positioning for radiotherapy is achievable.

Conclusions:

• The novel dental-fixated stereotactic frame provides accurate and reliable immobilization for fractionated SRT.
• This non-invasive method is suitable for high-precision radiotherapy requiring accurate localization and treatment delivery.
• The frame's adaptability to various imaging techniques enhances its utility in advanced radiation oncology.