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Updated: Jul 4, 2026

Mouse Models Of Helicobacter Infection And Gastric Pathologies
Published on: October 18, 2018
[Role of Helicobacter species in hepatobiliary diseases]
Maria Engedal Rasmussen1, Liv Ebbeskov Lauritsen, Leif Percival Andersen
1Rigshospitalet, Klinisk Mikrobiologisk Afdeling 9301.
Abstract:
Helicobacter species have been found in extragastric tissues of humans and mice, and it has been shown that hepatic infection with H. hepaticus causes chronic hepatitis and hepatocellular carcinoma (HCC) in mice. 18 studies of humans with hepatobiliary diseases have been reviewed. In studies of patients with HCC the results imply a pathogen role of Helicobacter species. The same trend was not found in studies of humans with other hepatobiliary diseases. There is no evidence of the possible involvement of Helicobacter species in the development of diseases in the hepatobiliary system.
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