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Related Experiment Video

Updated: Jul 4, 2026

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
08:26

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

An algorithm for identifying and classifying cerebral palsy in young children.

Karl C K Kuban1, Elizabeth N Allred, Michael O'Shea

  • 1Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, MA, USA. karl.kuban@bmc.org

The Journal of Pediatrics
|June 7, 2008
PubMed
Summary

A new algorithm classifies cerebral palsy (CP) subtypes in preterm infants. Quadriparesis is linked to higher impairment and co-morbidities like microcephaly and autism screening positivity compared to diparesis.

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Area of Science:

  • Neurology
  • Pediatrics
  • Developmental Pediatrics

Background:

  • Cerebral palsy (CP) affects children born prematurely, with varying subtypes impacting development.
  • Standardized classification of CP subtypes is crucial for research and clinical comparisons.

Purpose of the Study:

  • To develop a novel algorithm for classifying cerebral palsy subtypes.
  • To determine the prevalence of diparesis, hemiparesis, and quadriparesis in very preterm infants.
  • To compare the extent of handicap and co-morbidities across CP subtypes.

Main Methods:

  • A cohort of 2-year-old children born before 28 weeks gestation underwent a standardized neurological examination.
  • An algorithm was developed to classify children into CP subtypes: diparesis, hemiparesis, and quadriparesis.

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Related Experiment Videos

Last Updated: Jul 4, 2026

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
08:26

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy
07:20

Repeated Transcranial Magnetic Stimulation Combined with Action Observation Training in Children with Spastic Cerebral Palsy

Published on: August 9, 2024

  • Children were compared based on microcephaly, cognitive impairment (BSID-II), and autism screening (MCAT).

    • Main Results:

    • 11.4% of 1056 very preterm children had algorithm-classified CP.
    • Quadriparesis was the most prevalent subtype (52%), followed by diparesis (31%) and hemiparesis (17%).
    • Children with quadriparesis exhibited significantly higher rates of impairment, microcephaly, cognitive deficits, and autism screening positivity compared to those with diparesis.

    Conclusions:

    • A reliable algorithm for classifying CP subtypes in very preterm infants was successfully developed.
    • Quadriparesis is associated with the most severe gross motor dysfunction and highest rates of co-morbidities.
    • Diparesis appears to be the subtype with the least severe outcomes in this cohort.