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Related Concept Videos

Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

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Related Experiment Video

Updated: Jul 4, 2026

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center
07:48

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center

Published on: January 9, 2026

Delayed necrotizing acalculous cholecystitis after multiple trauma.

Christopher D Mann1, Matthew S Metcalfe, Christopher P Neal

  • 1Department of Surgery, University Hospitals of Leicester, Leicester Royal Infirmary, Leicester LE1 5WW, UK. chris.mann@doctors.org.uk

The American Journal of Emergency Medicine
|June 7, 2008
PubMed
Summary
This summary is machine-generated.

Necrotizing acalculous cholecystitis, a rare gallbladder inflammation without stones, can occur after severe orthopedic trauma. Prompt surgical treatment led to a successful outcome in this case report.

Related Experiment Videos

Last Updated: Jul 4, 2026

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center
07:48

Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center

Published on: January 9, 2026

Area of Science:

  • Medical Case Reports
  • Surgical Gastroenterology
  • Trauma Surgery

Background:

  • Necrotizing acalculous cholecystitis (NAC) is a severe gallbladder inflammation without gallstones.
  • NAC is an uncommon but serious complication, particularly in critically ill or trauma patients.
  • Prompt diagnosis and intervention are crucial for managing NAC.

Observation:

  • A case of NAC is presented in a patient 7 weeks post-multiple orthopedic trauma.
  • The patient presented with symptoms suggestive of acute abdominal pathology.
  • Diagnostic workup confirmed necrotizing acalculous cholecystitis.

Findings:

  • The patient underwent operative intervention for the diagnosed condition.
  • Surgical management involved gallbladder removal (cholecystectomy).
  • Histopathological examination confirmed necrotizing inflammation of the gallbladder.

Implications:

  • This case highlights that NAC can manifest weeks after significant orthopedic trauma.
  • Operative intervention is a viable and successful treatment strategy for NAC in this context.
  • Early recognition and surgical management are key to favorable outcomes in post-traumatic NAC.