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Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
Five- to 10-year results using a noncemented modular revision stem without bone grafting
Georg Köster1, Tim A Walde, Hans-Georg Willert
1Department of Orthopaedic Surgery, Clinic for Orthopaedic Surgery, Lorsch, Germany.
The Journal of Arthroplasty
|June 7, 2008
Summary
This study shows the modular uncemented revision stem (Profemur-R) is a viable option for hip revision surgery. It demonstrated good bone remodeling and a 96% survival rate over 10 years, improving patient hip function.
Area of Science:
- Orthopedic Surgery
- Biomaterials Engineering
- Reconstructive Surgery
Background:
- Revision hip arthroplasty addresses failed primary hip replacements.
- Femoral defects present challenges in revision surgery.
- Modular uncemented stems offer potential solutions for bone reconstruction.
Purpose of the Study:
- To evaluate the long-term (5-10 years) clinical and radiographic outcomes of the Profemur-R modular uncemented revision stem.
- To assess the efficacy of this implant in reconstructing femoral defects without bone grafting.
Main Methods:
- Prospective evaluation of 73 consecutive Profemur-R stem revisions.
- Assessment of functional outcomes using Harris hip score.
- Radiographic analysis of bone defect remodeling and implant stability.
- Calculation of implant survival rate with aseptic loosening as the endpoint.
Main Results:
- Average Harris hip score improved from 40 to 75.
- Complete bone defect remodeling in 70% of cases; partial in 30%.
- 96% survival rate at an average of 10 years, with only 2 cases of progressive subsidence and 3 rerevisions (1 septic).
Conclusions:
- The Profemur-R modular uncemented revision stem is a safe and effective option for femoral reconstruction in revision hip arthroplasty.
- The implant facilitates significant bone defect remodeling and provides durable fixation.
- It offers a viable solution for complex revision cases, improving functional outcomes.