Interaction between nitroheterocyclic compounds with beta-cyclodextrins: phase solubility and HPLC studies.

Nathalie F S de Melo1, Renato Grillo, André Henrique Rosa

  • 1Departamento de Engenharia Ambiental, Universidade Estadual Paulista Júlio de Mesquita Filho, Campus Sorocaba, Av. Três de Março 511, CEP 18087-180, Sorocaba, São Paulo, Brazil.

Summary

This study investigated cyclodextrin complexation of nitrofurazone (NF) and NFOH to improve Chagas disease treatments. Complexation enhances drug characterization, aiding the development of effective therapeutic options against Trypanosoma cruzi.

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