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Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel Disease...
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Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Related Experiment Video

Updated: Jul 4, 2026

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE
09:24

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE

Published on: April 15, 2014

Immunotherapy for neurological diseases.

Pablo Villoslada1, Beatriz Moreno, Ignacio Melero

  • 1Department of Neuroscience, Center for Applied Medical Research, University of Navarra, Pamplona, Spain. pvilloslada@unav.es

Clinical Immunology (Orlando, Fla.)
|June 7, 2008
PubMed
Summary
This summary is machine-generated.

Immunotherapies show promise for treating chronic neurological diseases by leveraging the immune system for brain repair. Further research is needed to understand specific pathologies and patient responses to ensure safe and effective treatments.

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Published on: September 1, 2018

Area of Science:

  • Neuroscience
  • Immunology
  • Therapeutics

Background:

  • Neurological diseases pose a significant health burden in Western societies, necessitating novel therapeutic strategies.
  • Emerging research highlights the immune system's role in brain damage and repair, positioning immunotherapy as a potential treatment avenue.
  • Advances in immune response manipulation technologies enhance the feasibility of developing immunotherapies for neurological conditions.

Purpose of the Study:

  • To explore the potential of immunotherapy as a treatment for chronic neurological diseases.
  • To investigate the immune system's role in neurological pathologies and its therapeutic manipulation.
  • To identify key considerations for applying immunotherapy in neurological disease treatment.

Main Methods:

  • Review of recent discoveries on neuroinflammation and immune system involvement in neurological diseases.
  • Analysis of technological advancements in immune response engineering.
  • Examination of immunotherapy applications in cancer and autoimmune diseases for comparative insights.

Main Results:

  • Immunotherapy presents a promising strategy for neurological disease treatment due to its potential for tissue repair and adaptable immune responses.
  • The immune system's dual role in causing and potentially repairing brain damage requires careful consideration.
  • Successful immunotherapy application necessitates a deep understanding of target pathologies and individual patient immune profiles.

Conclusions:

  • Immunotherapy holds significant potential for treating neurological diseases, mirroring successes in oncology and autoimmune disorders.
  • Precise understanding of neurological pathologies and patient-specific immune responses is crucial before clinical application.
  • Mitigating potential immune-mediated tissue damage is a primary safety concern for neuro-immunotherapies.