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Updated: Jul 4, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
C-reactive protein levels do not correlate with retinal artery occlusion but with atherosclerosis
N Goldenberg-Cohen1, Y Cohen, Y Monselise
1Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel. ncohen1@gmail.com
Purpose:
To determine C-reactive protein (CRP) levels in acute retinal artery occlusion (RAO) and their association with atherosclerotic risk factors.
Methods:
CRP levels in 16 patients with RAO were compared with levels in 16 age-matched controls at risk of atherosclerosis and 16 young volunteers. Repeated CRP testing was performed 6 years later.
Results:
Elevated CRP levels (>3 mg/l) and risk factors for atherosclerosis were detected in seven patients in the study group (44%) and nine at-risk controls (56%). On follow-up, CRP levels were reduced in all seven retested patients. Six patients died of vascular events within 5 years, of whom four had high CRP levels during RAO.
Conclusions:
CRP level correlates with atherosclerosis but it is not significantly elevated in patients with RAO.
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