Related Experiment Video
Updated: Jul 4, 2026

Juxtacellular Monitoring and Localization of Single Neurons within Sub-cortical Brain Structures of Alert, Head-restrained Rats
Published on: April 27, 2015
Coding of self-motion signals in ventro-posterior thalamus neurons in the alert squirrel monkey
Vladimir Marlinski1, Robert A McCrea
1Department of Neurobiology, Pharmacology and Physiology, University of Chicago, 947 E. 58th Street, MC0926, Chicago, IL 60637, USA. vmarlinski@gmail.com
Abstract:
The firing behavior of 47 ventro-posterior thalamus neurons was studied in two alert squirrel monkeys during rotations of whole body, head and trunk. A total of 27 of these neurons (57%) were sensitive to spatial motion of the head irrespective of the mode of motion. These neurons responded similarly when the head moved simultaneously with the trunk, and when the head voluntarily or involuntarily moved on the stationary trunk. These neurons did not respond to rotation of the trunk when the spatial position of the head was fixed. Five neurons (11%) responded only to involuntary movement of the head produced by external force, but were insensitive to voluntary spatial head movement. They also did not respond to spatial motion of the trunk. Totally 15 neurons (32%) were sensitive to spatial motion, which included rotation of the trunk. These neurons responded when the trunk moved alone, and when the trunk moved simultaneously with the head, but were not responsive to spatial movement of the head while the trunk was stationary. We suggest that the vestibulo-thalamo-cortical pathway comprises two distinct functional channels. In one of these channels, cephalokinetic, spatial motion of the head is coded. In the other channel, somatokinetic, motion of the body in space is coded. Each of these channels further consists of two divisions. In the principal division the motion signal is conveyed continuously, irrespective of the behavioral context of motion. In the other auxiliary division the signal only codes movement caused by externally applied force.
Related Concept Videos
Diencephalon: Thalamus and Information Relay
Major Somatic Sensory Pathways
Propagation of Action Potentials
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
Motor and Sensory Areas of the Cortex
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.

