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[The increased of alanine aminotransferase in rotavirus diarrhea]

Ewa Smukalska1, Małgorzata Pawłowska, Dorota Kozielewicz

  • 1Wojewódzki Szpital Obserwacyjno-Zakaźny w Bydgoszczy.

Przeglad Epidemiologiczny
|June 10, 2008
PubMed

Insights

Retrovirus diarrhea in children can cause elevated alanine aminotransferase (ALT) levels, indicating liver activity changes. This study analyzed 97 pediatric cases, finding ALT elevations in 25% without other liver issues.

Area of Science:

  • Pediatric Gastroenterology
  • Hepatology
  • Infectious Diseases

Context:

  • Retrospective analysis of 97 children treated for retrovirus diarrhea.
  • Focus on liver activity and alanine aminotransferase (ALT) levels.
  • Study conducted at Observation and Liver Diseases Unit in Bydgoszcz, June 2006.

Purpose:

  • To assess liver activity in children with retrovirus diarrhea.
  • To evaluate the prevalence and characteristics of hypertransaminasemia in this cohort.
  • To determine the duration, intensity, and timing of elevated ALT levels.

Summary:

  • 25% of analyzed pediatric cases with retrovirus diarrhea exhibited elevated ALT.
  • Elevated ALT levels persisted from 7 days to 6 months.
  • No other liver function disturbances were observed in these cases.

Impact:

  • Highlights potential hepatic involvement in pediatric retrovirus diarrhea.
  • Provides data on the incidence and duration of ALT elevation.
  • Informs clinical monitoring and management of liver function in affected children.

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