Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 4, 2026

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications
05:20

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications

Published on: May 31, 2018

Recent developments in cyclic acetal biomaterials for tissue engineering applications.

Erin E Falco1, Minal Patel, John P Fisher

  • 1Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, Maryland 20742, USA.

Pharmaceutical Research
|June 10, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the use of family health histories in the African American community to reduce health disparities: Protocol for a randomized controlled trial.

Contemporary clinical trials·2026
Same author

Large-scale manufacturing of precisely patterned flexible soft tissue implants with high porosity.

Biofabrication·2026
Same author

Roadmap on biomaterials for women's health.

JPhys materials·2026
Same author

Newborn Vitals in the First 10 min Do Not Differ With Mode of Delivery.

International journal of pediatrics·2026
Same author

Rapid prediction of cerebral edema on CT scan after traumatic brain injury.

Trauma surgery & acute care open·2026
Same author

Feasibility of Mini-Clinical Evaluation Exercise as a Workplace-Based Assessment Tool for Respiratory Medicine Interns: A Prospective Interventional Study.

Cureus·2026

Novel cyclic acetal biomaterials offer improved biocompatibility for tissue engineering. These advanced materials minimize inflammatory responses, making them promising for hard and soft tissue repair and bone regeneration.

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Tissue Engineering

Background:

  • Synthetic biomaterials are crucial for tissue engineering, offering tailored properties like biocompatibility and mechanical strength.
  • Conventional ester-based polymers can release acidic byproducts, causing adverse in vivo reactions.
  • Developing inert synthetic polymers with controlled degradation is essential for safe and effective biomedical applications.

Purpose of the Study:

  • To introduce a novel class of cyclic acetal-based biomaterials.
  • To evaluate their suitability for hard and soft tissue engineering applications.
  • To review recent advancements in cyclic acetal biomaterials and their therapeutic potential.

Main Methods:

  • Fabrication of scaffolds from cyclic acetal-based polymers.

More Related Videos

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture
08:28

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture

Published on: May 26, 2016

Postproduction Processing of Electrospun Fibres for Tissue Engineering
15:52

Postproduction Processing of Electrospun Fibres for Tissue Engineering

Published on: August 9, 2012

Related Experiment Videos

Last Updated: Jul 4, 2026

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications
05:20

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications

Published on: May 31, 2018

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture
08:28

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture

Published on: May 26, 2016

Postproduction Processing of Electrospun Fibres for Tissue Engineering
15:52

Postproduction Processing of Electrospun Fibres for Tissue Engineering

Published on: August 9, 2012

  • Comprehensive characterization of scaffold properties (e.g., mechanical, degradation).
  • In vivo assessment of biocompatibility and inflammatory response in bone defect models.

    • Main Results:

    • Successful fabrication of cyclic acetal scaffolds for hard and soft tissue replacement.
    • Demonstrated minimal inflammatory response and promotion of bone growth in repair applications.
    • Cyclic acetals exhibit favorable biocompatibility compared to traditional ester-based polymers.

    Conclusions:

    • Cyclic acetal biomaterials represent a promising advancement over conventional synthetic polymers.
    • These materials show significant potential for diverse tissue engineering applications, including bone regeneration.
    • Further research into polyacetals and polyketals for drug delivery is warranted.