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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Chronic lung disease in newborns
M Jeeva Sankar1, Ramesh Agarwal, Ashok K Deorari
1Division of Neonatology, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Bronchopulmonary dysplasia (BPD), a chronic lung disease in preterm infants, arises from prematurity and respiratory support. Current management strategies offer limited benefits, necessitating evidence-based protocols.
Area of Science:
- Neonatology
- Pediatric Pulmonology
- Developmental Biology
Background:
- Bronchopulmonary dysplasia (BPD) is a chronic lung disease affecting preterm infants requiring respiratory support.
- Risk factors include prematurity, oxygen therapy, ventilation, infections, patent ductus arteriosus, and genetic factors.
- Modern BPD presents as a milder form with impaired alveolar development, differing from historical severe inflammatory types.
Purpose of the Study:
- To review and discuss current evidence-based strategies for the prevention and treatment of bronchopulmonary dysplasia.
- To outline a comprehensive management protocol for BPD.
Main Methods:
- Literature review of pharmacological and ventilatory interventions for BPD.
- Synthesis of current evidence to inform management guidelines.
Main Results:
- Many established pharmacological and ventilatory strategies have shown limited efficacy in preventing or treating BPD.
- A shift towards milder forms of BPD characterized by arrested lung development is observed.
Conclusions:
- Effective BPD management requires a comprehensive, evidence-based approach.
- Further research is needed to identify beneficial interventions for BPD.
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