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Fibromyalgia and cognition.

Jennifer M Glass1

  • 1Substance Abuse Section, Department of Psychiatry, University of Michigan Medical School, Ann Arbor, USA. jglass@umich.edu

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|June 27, 2008
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Summary
This summary is machine-generated.

Fibromyalgia patients experience significant cognitive impairments, including memory deficits, that resemble aging. These "fibrofog" symptoms require further research for standardized testing and treatment.

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Area of Science:

  • Neuroscience
  • Psychology
  • Rheumatology

Background:

  • Fibromyalgia is frequently associated with patient-reported cognitive dysfunction, often termed "fibrofog."
  • Previous research confirms the incidence of cognitive problems in fibromyalgia patients through objective testing.

Purpose of the Study:

  • To investigate and confirm the existence and nature of cognitive impairments in fibromyalgia patients.
  • To characterize the specific domains of cognitive function affected by fibromyalgia.

Main Methods:

  • Utilized objective tests assessing metamemory, working memory, semantic memory, attention, task switching, and selective attention.
  • Compared cognitive performance in fibromyalgia patients to normative data, including age-related changes.

Main Results:

  • Fibromyalgia patients exhibit significant impairments in working, episodic, and semantic memory.
  • These memory deficits are comparable to approximately 20 years of aging.
  • Difficulties are exacerbated when tasks are complex and attention is divided.

Conclusions:

  • Objective evidence supports the presence of cognitive deficits in fibromyalgia, impacting memory and attention.
  • The cognitive impairments observed mimic accelerated aging, highlighting a significant disease burden.
  • Further research is needed to clarify the role of associated factors and establish standardized diagnostic and treatment protocols.