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Multifocal desmoplastic noninfantile astrocytoma
K Santhosh1, C Kesavadas, V V Radhakrishnan
1Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum 695011, India.
Journal of Neuroradiology = Journal De Neuroradiologie
|June 10, 2008
Summary
Multifocal desmoplastic astrocytoma is exceptionally rare in children. This case report details MRI findings and discusses the tumor
Area of Science:
- Pediatric neuro-oncology
- Neuroradiology
- Surgical neuropathology
Background:
- Desmoplastic astrocytoma is a rare glial tumor, typically diagnosed in infancy.
- Non-infantile desmoplastic astrocytoma is exceedingly rare, with limited case reports.
- Multifocal presentation at initial diagnosis is highly unusual for this tumor type.
Observation:
- An 11-year-old child presented with multifocal desmoplastic astrocytoma.
- Magnetic Resonance Imaging (MRI) revealed characteristic tumor appearances.
- Tumor origin was suggested to be leptomeningeal or superficial cortical.
Findings:
- MRI findings supported a primary leptomeningeal or superficial cortical origin.
- Cystic formations were attributed to cerebrospinal fluid entrapment.
- The differential diagnosis included metastases versus metachronous lesions.
Implications:
- This case expands the understanding of desmoplastic astrocytoma in older children.
- The findings contribute to the discussion on tumor development mechanisms.
- Further research is needed to clarify the behavior and treatment of rare pediatric brain tumors.
