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Updated: Jul 4, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
Published on: February 21, 2018
Hematopoietic lineage commitment: miRNAs add specificity to a widely expressed transcription factor
1Institute of Biomedical Research, University of Birmingham Medical School, Edgbaston, Birmingham B15 2TT, UK.
Abstract:
MicroRNAs are important regulators of normal and malignant hematopoiesis. A paper by Lu et al. in this issue of Developmental Cell demonstrates how one microRNA, miR-150, plays a critical role in commitment of the erythroid-megakaryocyte progenitor by modulating the level of the widely expressed transcription factor MYB (or c-Myb).
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