Related Experiment Video
Updated: Jul 4, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Outcome of sarcoidosis
Sonoko Nagai1, Tomohiro Handa, Yutaka Ito
1Central Clinic/Research Center, Masuyacho 56-58, Sanjou-Takakura, Nakagyoku, Kyoto, Japan. nagai@chuo-c.jp
Abstract:
Sarcoidosis is a chronic granulomatous inflammatory disease of unknown etiology with heterogeneous outcome. Based on the natural history or clinical treatment course, the outcomes of cases can be divided into two wings: spontaneous regression (self-limited disease) or progression of extensive fibrotic lesions as a postgranulomatous fibrosis. In addition to examining these outcomes, this article focuses on several related concepts, including chronicity (persistence of the lesions), relapse/recurrence, deterioration, and mortality. It also reviews the outcomes from the point of view of relevant clinical phenotypes, the natural disease course, the effects of treatment, and the effects of lung transplantation. Finally, it considers the effects of pulmonary hypertension, various genetic factors on the outcomes, and the efficacy of several novel therapeutic drugs in treating sarcoidosis.
Related Concept Videos
Rocky Mountain Spotted Fever
Rheumatic Heart Disease I: Introduction
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Cardiomyopathy IV: Restrictive Cardiomyopathy
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Cushing Syndrome II: Pathophysiology