Related Experiment Video
Updated: Jul 4, 2026

09:00
Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke
Published on: February 10, 2023
Arterial occlusion using a microguidewire as a radiofrequency electrode
Byung Kook Kwak1, Hyung Jin Shim
1Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea. kwakbk@cau.ac.kr <kwakbk@cau.ac.kr>
Summary
Superselective radiofrequency (RF) energy delivery using a microguidewire effectively occluded diseased arteries in most cases. Further refinement is needed to prevent complications and optimize RF ablation for arterial embolization.
Area of Science:
- Interventional Radiology
- Vascular Surgery
- Medical Device Technology
Background:
- Arterial embolization is a common procedure for treating various vascular conditions.
- Current embolization techniques may have limitations in achieving complete and targeted vessel occlusion.
- Superselective delivery of energy offers a potential advancement in minimally invasive vascular treatments.
Observation:
- A novel technique utilizing a microcatheter and a specialized microguidewire for superselective radiofrequency (RF) energy delivery was employed.
- The microguidewire tip acted as an electrode to deliver RF energy for arterial occlusion.
- The technique was applied to four cases, including renal branch arteries and an arteriovenous malformation.
Findings:
- Successful arterial occlusion was achieved in three out of four cases using RF energy delivery.
- One case required supplementary embolization agents for complete occlusion.
- No complications were reported, and sustained occlusion of the treated lesions was observed.
Implications:
- This microguidewire-based RF energy delivery presents a viable endovascular approach for arterial occlusion.
- Further technical development is necessary to address wire adhesion and optimize RF energy delivery to adjacent structures.
- This technique holds promise for improving embolization procedures with potential for reduced invasiveness and enhanced efficacy.

