Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Veins of Head and Neck01:19

Veins of Head and Neck

The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cytokine markers in intracerebral hemorrhage are linked to ventricular imaging and outcomes.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same author

Hematoma Interleukin-1 Receptor Antagonist Concentrations Predict Long-Term Outcome in Acute Human Intracerebral Hemorrhage.

Annals of neurology·2026
Same author

Single-Cell Analysis of Microglia and Monocyte Dynamics Uncover Distinct TNF-α-driven Neuroimmune Signatures after Intracerebral Hemorrhage.

bioRxiv : the preprint server for biology·2026
Same author

Characterizing inflammatory biomarkers in post-stroke seizure risk and outcome prognostication.

PloS one·2026
Same author

Distinct Inflammatory Profiles in Angiography-Negative Subarachnoid Hemorrhage: A Focused Case Series.

medRxiv : the preprint server for health sciences·2026
Same author

Cross-Platform Proteomics and Machine Learning Algorithms Nominate Plasma Biomarkers of Stroke Diagnosis.

Journal of the American Heart Association·2026

Related Experiment Videos

Obstructive hydrocephalus from venous sinus thrombosis.

Michael T Mullen1, Lauren H Sansing, Robert W Hurst

  • 1Department of Neurology, Hospital of the University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19103, USA. Michael.Mullen@uphs.upenn.edu.

Neurocritical Care
|June 11, 2008
PubMed
Summary
This summary is machine-generated.

Cerebral venous sinus thrombosis (CVST) can rarely cause hydrocephalus. Urgent endovascular treatment to restore blood flow may negate the need for an external ventricular drain in these rare CVST cases.

Related Experiment Videos

Area of Science:

  • Neurology
  • Vascular Neurology
  • Neurosurgery

Background:

  • Cerebral venous sinus thrombosis (CVST) is an uncommon type of stroke.
  • Increased intracranial pressure is a known complication of CVST.
  • Hydrocephalus is a rarely reported complication of CVST.

Observation:

  • A 49-year-old woman presented with headache, vomiting, and neurological decline.
  • Cranial CT and MRI revealed extensive CVST and hydrocephalus.
  • The patient was treated with anticoagulation and endovascular thrombolysis, without an external ventricular drain.

Findings:

  • The patient experienced a significant recovery with a normal neurological examination.
  • Successful recanalization of thrombosed sinuses was achieved.
  • Hydrocephalus resolved without surgical intervention.

Implications:

  • Hydrocephalus is a rare but serious complication of CVST.
  • Endovascular treatment to recanalize venous sinuses may prevent the need for an external ventricular drain.
  • This case highlights a potential management strategy for CVST-associated hydrocephalus.