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Updated: Jul 4, 2026

miRNA Expression Analyses in Prostate Cancer Clinical Tissues
11:29

miRNA Expression Analyses in Prostate Cancer Clinical Tissues

Published on: September 8, 2015

[Recent progress on miRNAs in the pathogenesis of colon cancer]

Jie-ting Tang1, Jing-yuan Fang

  • 1Shanghai Institution of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200001 People's Republic of China.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics
|June 11, 2008
PubMed

Insights

MicroRNAs (miRNAs) are key epigenetic regulators in colorectal cancer. This review explores their expression profiles and regulatory networks for novel anticancer therapies.

Area of Science:

  • Molecular Biology
  • Genetics
  • Cancer Research

Context:

  • MicroRNAs (miRNAs) are small, noncoding RNA molecules regulating gene expression.
  • Colorectal cancer is a complex disease with both genetic and epigenetic components.
  • miRNA dysregulation is increasingly recognized in cancer pathogenesis.

Purpose:

  • To review recent advances in colorectal miRNA expression profiles.
  • To discuss the regulatory network of miRNAs in colon cancer initiation and progression.
  • To highlight the potential of miRNA-based epigenetic therapy for colorectal cancer.

Summary:

  • This review synthesizes current knowledge on colorectal cancer miRNA expression patterns.
  • It details the role of specific miRNAs in the molecular mechanisms of colon carcinogenesis.
  • The discussion emphasizes how miRNAs contribute to the epigenetic landscape of colorectal cancer.

Impact:

  • Provides a comprehensive overview of miRNAs in colorectal cancer.
  • Identifies key miRNA targets and pathways for therapeutic intervention.
  • Advances the understanding of epigenetic mechanisms in cancer treatment strategies.

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