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[Acute multifocal placoid pigment epiteliopathy]
Oftalmologia (Bucharest, Romania : 1990)
|June 12, 2008
Summary
Acute multifocal placoid pigment epitheliopathy (AMPPE) can present atypically, as seen in a young patient with bilateral lesions. This case highlights rare complications like choroidal neovascularization and asymmetry, impacting visual acuity.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Immunology
Background:
- Acute multifocal placoid pigment epitheliopathy (AMPPE) is a rare condition with unclear causes, potentially linked to systemic inflammation.
- The typical presentation involves bilateral placoid retinal lesions.
Observation:
- A young patient presented with bilateral AMPPE, showing varied lesion stages: cicatricial in the right eye and mixed active/cicatricial in the left.
- Past infections with cytomegalovirus and toxoplasma were noted.
- Fluorescein angiography revealed characteristic early hypofluorescence and late hyperfluorescence.
Findings:
- Unique atypical findings included choroidal neovascularization in the left eye, a rare occurrence in AMPPE but common in serpiginous choroidopathy.
- The patient experienced recurrences and significant asymmetry between eyes.
- Visual acuity was markedly reduced in the right eye (1/10), with the left macula threatened by neovascularization.
Implications:
- This case expands the understanding of AMPPE's atypical presentations and potential complications.
- It underscores the importance of vigilant monitoring for neovascularization and asymmetry in AMPPE patients.
- Further research into AMPPE's etiology and pathogenesis is warranted to guide treatment strategies.
