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Related Experiment Videos

Intermediate filament-associated proteins.

R Foisner1, G Wiche

  • 1Institute of Biochemistry, University of Vienna, Austria.

Current Opinion in Cell Biology
|February 1, 1991
PubMed
Summary

Intermediate filament-associated proteins are newly identified proteins interacting with intermediate filaments. Research highlights their specific expression, location, and roles in different cells and tissues.

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Area of Science:

  • Cell biology
  • Protein biochemistry

Background:

  • Intermediate filaments (IFs) are crucial cytoskeletal components.
  • A growing number of proteins are identified as interacting with IFs.

Purpose of the Study:

  • To review recent findings on intermediate filament-associated proteins (IFAPs).
  • To emphasize IFAP tissue/cell type-specific expression, subcellular localization, and functions.

Main Methods:

  • Literature review of recently published data.
  • Analysis of protein identification and characterization studies.

Main Results:

  • Identification and characterization of novel IFAPs.
  • Data on tissue/cell type-specific expression patterns.
  • Information on subcellular distribution of IFAPs.

Conclusions:

  • IFAPs represent a diverse group of proteins with specific roles.
  • Understanding IFAPs is key to comprehending cytoskeletal regulation and cell function.

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