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Related Experiment Video

Updated: Jul 4, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Postrefractive surgery dry eye.

Guilherme G Quinto¹, Walter Camacho, Ashley Behrens

¹The Wilmer Ophthalmological Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-0005, USA.

Current Opinion in Ophthalmology

|June 12, 2008

Summary

Dry eye is a common complication following refractive surgery due to corneal nerve damage. Treatments like cyclosporine and punctal occlusion show promise, with femtosecond lasers potentially reducing dry eye symptoms.

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Last Updated: Jul 4, 2026

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Area of Science:

Ophthalmology
Ocular Surface Disease
Refractive Surgery

Background:

Refractive surgery, including photorefractive keratectomy and laser in-situ keratomileusis, can lead to ocular surface changes.
Damage to corneal sensory nerves is a known consequence, affecting tear secretion and tear film stability.

Purpose of the Study:

To review recent literature on ocular surface alterations post-refractive surgery.
To evaluate treatment outcomes for dry eye disease occurring after refractive surgery.

Main Methods:

Literature review of published studies.
Analysis of treatment modalities for post-refractive surgery dry eye.

Main Results:

Cyclosporine, an FDA-approved agent, shows positive results for chronic dry eye.
Combined cyclosporine and punctal occlusion may offer additive benefits.
Femtosecond laser-assisted in-situ keratomileusis (LASIK) may result in fewer dry eye symptoms, possibly due to thinner flap creation.

Conclusions:

Dry eye is a frequent complication after photorefractive keratectomy and LASIK.
Pre-existing dry eye requires ocular surface management before refractive surgery.
Addressing corneal nerve damage and tear film instability is crucial for managing post-refractive surgery dry eye.