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Raman Spectroscopy Instrumentation: Overview

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A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
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Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

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Published on: May 16, 2022

Near-field Raman imaging using optically trapped dielectric microsphere.

Johnson Kasim¹, Yu Ting, You Yu Meng

¹Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang TechnologicalUniversity, 1 Nanyang Walk, Blk 5 Level 3, Singapore.

|June 12, 2008

Summary

Researchers developed a new near-field Raman imaging technique using a polystyrene microsphere. This method achieves 80 nm spatial resolution, overcoming diffraction limits for nanoscience applications.

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Area of Science:

Nanoscience and Nanotechnology
Optical Microscopy
Materials Science

Background:

Diffraction-limited spatial resolution is a major challenge in Raman imaging for nanoscience.
Existing near-field Raman techniques, such as aperture and apertureless methods, have limitations.

Purpose of the Study:

To introduce a novel near-field Raman imaging approach.
To achieve enhanced spatial resolution beyond the diffraction limit.

Main Methods:

Trapping and scanning a polystyrene microsphere over the sample surface in an aqueous environment.
Utilizing the microsphere as a near-field probe for Raman signal enhancement.

Main Results:

Achieved a spatial resolution of approximately 80 nm.
Successfully resolved fine structures of PMOS transistors with SiGe source drain stressors and poly-Si gates.
Demonstrated imaging of gold nanopatterns with high reproducibility.

Conclusions:

The polystyrene microsphere-based near-field Raman imaging technique offers a viable solution for high-resolution imaging in nanotechnology.
This method provides excellent reproducibility and can resolve nanoscale features relevant to semiconductor devices and nanostructures.