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[Periapical odontogenic processes of inflammatory origin. Enzyme activity]
M J García-Pola Vallejo1, M E Rodriguez Rossel, J S López Arranz
1Escuela de Estomatología, Universidad de Oviedo.
Revista De Actualidad Odontoestomatologica Espanola : Boletin De Informacion, Del Ilustre Consejo General De Colegios De Odontologos Y Estomatologos De Espana
|April 1, 1991
Summary
This histoenzymological study found elevated acid phosphatase, lactate dehydrogenase (LDH), and glucose-6-phosphate dehydrogenase (G6PDH) in periapical granulomas and inflammatory cysts. These enzyme variations indicate distinct cellular activity in oral inflammatory conditions.
Area of Science:
- Oral pathology
- Biochemistry
- Histology
Context:
- Investigated histoenzymological variations in oral lesions.
- Examined 40 tissue specimens: normal oral mucosa, periapical granulomas, and inflammatory cysts.
Purpose:
- To analyze significant variations in oxidative and hydrolase enzyme activities.
- To understand enzymatic differences in periapical lesions.
Summary:
- Enzymatic activities in inflammatory cysts mirrored normal epithelium.
- Elevated acid phosphatase, LDH, and G6PDH observed in granuloma cells and cyst-lining epithelium.
- Distinct glycosaminoglycan activity patterns were noted across different epithelial types.
Impact:
- Provides insights into the biochemical processes underlying periapical lesions.
- Highlights specific enzyme markers associated with oral inflammation.
- Contributes to understanding cellular behavior in pathological oral tissues.
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