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Related Experiment Videos

Design optimization of continuous sterilizers.

M H Ashley1, J G Mooyman

  • 1John Brown Engineers & Constructors Limited, 1 Buckingham Street, Portsmouth, England P01 1HN.

Biotechnology and Bioengineering
|July 1, 1982
PubMed
Summary
This summary is machine-generated.

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This study presents a continuous sterilization design using thermal deactivation data for infecting organisms. It includes engineering design optimization for cost-effectiveness and explores membrane filtration systems.

Area of Science:

  • Microbiology
  • Biotechnology
  • Chemical Engineering

Background:

  • Continuous sterilization is crucial for microbial control in various industries.
  • Optimizing sterilization processes balances efficacy with economic factors.

Purpose of the Study:

  • To develop and optimize a continuous sterilization design.
  • To evaluate thermal deactivation kinetics and engineering design parameters.
  • To investigate membrane filtration as an alternative sterilization method.

Main Methods:

  • Analysis of practical temperature/time data for thermal deactivation of microorganisms.
  • Engineering design optimization focusing on capital and operating costs.
  • Consideration of continuous sterilization systems utilizing membrane filtration.

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Main Results:

  • A continuous sterilization design incorporating thermal deactivation data was developed.
  • Engineering design optimization demonstrated cost-effectiveness.
  • Membrane filtration emerged as a viable alternative for continuous sterilization.

Conclusions:

  • The proposed continuous sterilization design offers an optimized approach for microbial control.
  • Cost-effective engineering solutions are achievable through process optimization.
  • Membrane filtration presents a promising alternative for continuous sterilization applications.