[Chronobiological aspects of gerontology]
Related Experiment Video
Updated: Jul 4, 2026

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
Published on: April 7, 2020
Abstract:
The hypothesis of the dynamics of aging on the chronobiological grounds is presented. The results of the original research are demonstrated as well as the conclusions made by the leading authorities in the human individual annual and perennial endogenous cycles are treated. Risk-zones, which tend to increase the possibility of "mistakes" in a genetic program that lead to aging of organism are proposed. The data obtained could provide an opinion of existing both the perennial and annual endogenous cycles, that begin from the moment of conception and include nine months of the embryo period and three months after the date of birth. The data available provide a ground for a hypothesis verifying the trimester time-genetic program of the endogenous year. The "mistakes" in the chronobiological program emerging as the reaction on the environment during the periods of intensive growth of metabolic process are supposed to be one of the essential causes of aging and early death.
Related Concept Videos
Pharmacodynamics in Geriatric Patients: Effects of Age
Circadian Rhythms and Gene Regulation
Circadian Rhythms and Gene Regulation
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Biological Clocks and Seasonal Responses