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Updated: Jul 4, 2026

A Modified Murine Heterotopic Heart Transplant Protocol Matching Contemporary Standards of Aseptic Technique, Anesthesia, and Analgesia
Published on: September 28, 2022
[Anesthesia for a patient with Cushing's disease and hepatitis B]
Sachiko Nao1, Yushi Adachi, Shigehito Sato
1Department of Anesthesiology, Intensive Care Unit of University Hospital, Hamamatsu University School of Medicine, Hamamatsu.
Abstract:
A 34-year-old female patient complaining of general fatigue and liver dysfunction was diagnosed as acute aggravation of chronic hepatitis B. She showed a complication of Cushing's disease and hepatitis was initially treated with lamivudine administration as well as inhibition and supplementation of cortisol, because hypercortisolemia could induce massive liver necrosis with hepatitis. After inducing remission phase, Hardy's operation for pituitary microadenoma was scheduled. Induction and maintenance of anesthesia were achieved by administration of propofol and analgesia was attained by intermittent administration of fentanyl. Liver function was well maintained during perioperative period and no complication concerning anesthesia was observed.
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