Related Experiment Video

Updated: Jul 4, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

Complex partial status epilepticus in children with epilepsy

Kenichi Kikumoto1, Harumi Yoshinaga, Katsuhiro Kobayashi

  • 1Department of Child Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama 700-8558, Japan. kkikumoto@mac.com

Brain & Development
|June 13, 2008
PubMed

Insights

Diagnosing complex partial status epilepticus (CPSE) in children requires careful observation of subtle symptoms and EEG findings. This study clarifies CPSE characteristics in pediatric epilepsy patients.

Area of Science:

  • Pediatric Neurology
  • Epileptology
  • Clinical Neurophysiology

Background:

  • Complex partial status epilepticus (CPSE) is frequently underdiagnosed in pediatric populations.
  • Understanding the nuances of CPSE presentation in children is crucial for timely diagnosis and management.

Purpose of the Study:

  • To elucidate the clinical characteristics and underlying pathophysiology of CPSE in children with epilepsy.
  • To improve diagnostic accuracy for CPSE in pediatric patients.

Main Methods:

  • Retrospective review of medical records and electroencephalograms (EEGs) from 17 children diagnosed with CPSE.
  • Analysis of clinical symptoms, EEG patterns (ictal and postictal), and estimated epileptogenic zones.

Main Results:

  • CPSE was diagnosed in children aged 3 months to 17 years, often associated with various epilepsy types.
  • Subtle symptoms (autonomic disturbances, altered consciousness) were prominent in many CPSE episodes, sometimes with minor or major motor elements.
  • Ictal EEG patterns varied, including spike-dominant and spike/high-voltage slow wave mixes, even with subtle clinical signs. Epileptogenic zones showed variability, with a majority not originating from the temporal lobe.

Conclusions:

  • Accurate diagnosis of CPSE in children necessitates close monitoring of subtle clinical symptoms and mild convulsive elements.
  • Integration of ictal EEG findings is essential for diagnosing CPSE, especially when clinical presentation is ambiguous.
Abstract

More Related Videos

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

Related Concept Videos

Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...