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Methods for Intravenous Self Administration in a Mouse Model
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A demonstration of intravenous nicotine self-administration in humans?

Heather G Fulton, Sean P Barrett

    Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
    |June 13, 2008
    PubMed
    Abstract

    No abstract available in PubMed .

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    Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating sympathetic or...

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