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Updated: Jul 4, 2026

A Novel Bioreactor for High Density Cultivation of Diverse Microbial Communities
Published on: December 25, 2015
Mixing and oxygen transfer in conventional stirred fermentors
R Manfredini1, V Cavallera, L Marini
1Farmitalia, C. Erba S.p.A., Prod., Bios. Bioingegneria, Settimo Torinese, Italy.
Abstract:
A set of experiments has been performed in an industrial 112 m(3) fermentor in order to get a complete map of oxygen concentration and temperature distribution in the system. Five fermentations of non-Newtonian broths of two different strains, in various operating conditions, were examined. A simple model has been developed which takes into account both the mixing and the mass-transfer properties of the fermentor, and a dimensionless parameter has been identified which is sufficient to characterize the oxygen axial distribution in the reactor in any operating condition.
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