X-ray photoelectron spectroscopy analysis of the surface chemical structure of some biodegradable poly(orthoesters)

The surface analysis of some biodegradable poly(orthoesters) has been undertaken using X-ray photoelectron spectroscopy (XPS). There is very good agreement between the experimental and theoretical surface compositions. All the carbon environments of the poly(orthoesters) are detected within the high-resolution C1s peak envelopes and again, good agreement is observed between the theoretical and experimental proportions of each carbon environment. The data confirm the high surface purity of these polymers and demonstrate the potential for the use of XPS in future studies of the solid state in-situ degradation of poly(orthoesters).