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Related Concept Videos

Uncertainty: Overview00:59

Uncertainty: Overview

In analytical chemistry, we often perform repetitive measurements to detect and minimize inaccuracies caused by both determinate and indeterminate errors. Despite the cares we take, the presence of random errors means that repeated measurements almost never have exactly the same magnitude. The collective difference between these measurements - observed values - and the estimated or expected value is called uncertainty. Uncertainty is conventionally written after the estimated or expected value.
Propagation of Uncertainty from Random Error00:59

Propagation of Uncertainty from Random Error

An experiment often consists of more than a single step. In this case, measurements at each step give rise to uncertainty. Because the measurements occur in successive steps, the uncertainty in one step necessarily contributes to that in the subsequent step. As we perform statistical analysis on these types of experiments, we must learn to account for the propagation of uncertainty from one step to the next. The propagation of uncertainty depends on the type of arithmetic operation performed on...
Uncertainty: Confidence Intervals00:54

Uncertainty: Confidence Intervals

The confidence interval is the range of values around the mean that contains the true mean. It is expressed as a probability percentage. The interpretation of a 95% confidence interval, for instance, is that the statistician is 95% confident that the true mean falls within the interval. The upper and lower limits of this range are known as confidence limits. The confidence limits for the true mean are estimated from the sample's mean, the standard deviation, and the statistical factor 't,' or...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Propagation of Uncertainty from Systematic Error01:10

Propagation of Uncertainty from Systematic Error

The atomic mass of an element varies due to the relative ratio of its isotopes. A sample's relative proportion of oxygen isotopes influences its average atomic mass. For instance, if we were to measure the atomic mass of oxygen from a sample, the mass would be a weighted average of the isotopic masses of oxygen in that sample. Since a single sample is not likely to perfectly reflect the true atomic mass of oxygen for all the molecules of oxygen on Earth, the mass we obtain from this particular...
Uncertainty in Measurement: Accuracy and Precision03:37

Uncertainty in Measurement: Accuracy and Precision

Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value.

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Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
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Identifying uncertainties to prioritise research.

Brian Buckley1

  • 1Department of General Practice, National University of Ireland, Galway.

Nursing Times
|June 14, 2008
PubMed
Summary

The James Lind Alliance identified and prioritized treatment uncertainties in urinary incontinence care. This aims to guide publicly funded research for better patient outcomes.

Area of Science:

  • Urology
  • Healthcare Research
  • Patient Advocacy

Background:

  • Urinary incontinence affects a significant population, leading to reduced quality of life.
  • There is a need to align research efforts with the priorities of patients and clinicians.

Purpose of the Study:

  • To identify and prioritize key uncertainties in urinary incontinence (UI) treatment.
  • To inform and direct publicly funded research initiatives.

Main Methods:

  • Collaboration with the James Lind Alliance (JLA).
  • Systematic identification of treatment uncertainties through stakeholder engagement.
  • Prioritization of identified uncertainties via a structured process.

Main Results:

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  • A ranked list of treatment uncertainties in urinary incontinence care was established.
  • The project successfully engaged patients, caregivers, and healthcare professionals.

    • Conclusions:

    • Prioritizing research based on patient-reported outcomes is crucial.
    • This initiative provides a clear roadmap for future research funding in urinary incontinence.