Related Experiment Video
Updated: Jul 4, 2026

Minimally Invasive Surgical Decompression of Occipital Nerves
Published on: September 13, 2024
The first 5 minutes after greater occipital nerve block
William Young1, Brianna Cook, Shahram Malik
1Thomas Jefferson University-Neurology, Philadelphia, PA 19107, USA.
Abstract:
We performed greater occipital nerve blocks on 24 migraineurs with unilateral migraine and trigeminal nerve distribution allodynia. Using a visual analog scale for migraine pain, brush allodynia in the trigeminal nerve distribution and photophobia were reduced 64%, 75%, and 67%, respectively, after 5 minutes. Allodynia improved faster than headache. The results of this study suggest that greater occipital nerve blocks initiate an inhibitory process that shuts down several symptom generators.
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