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Updated: Aug 24, 2026

A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology
Published on: June 3, 2014
[The characteristics of osteogenesis under conditions of stretch tension]
Abstract:
Structure of rough-fibrillar, netted and laminated bone tissues, formed in distraction regenerates on various stages of leg lengthening, was studied experimentally on dogs, using light, transmission and scanning electron microscopy and electron probe microassay. It was ascertained, that the first two types of tissues belong to the category of provisory, rapidly renewing ones, the volume increase of which is possible not only at the expense of appositional growth but also interstitially. Their formation in the area of the regenerate, more proximally and more distally than the medial layer, provided longitudinal growth of primary osteons forming here and thereby the growth of the whole bone regenerate.
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