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Updated: Jul 4, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
When should abdominal magnetic resonance imaging be used?
José A Gonçalves Neto1, Mohamed Elazzazzi, Ersan Altun
1Department of Radiology, University of North Carolina, Chapel Hill, North Carolina 27514, USA. neto_goncalves@yahoo
Patient safety is now a key factor in choosing imaging studies, alongside diagnostic accuracy and cost. Magnetic resonance imaging (MRI) offers advantages for certain conditions, especially in radiation-sensitive patients.
Area of Science:
- Radiology
- Medical Imaging
- Patient Safety
Background:
- Historically, imaging study selection prioritized diagnostic accuracy and cost.
- Increasing awareness of radiation-induced cancer risks from computed tomography (CT) necessitates a reevaluation of imaging practices.
- A new paradigm emphasizes patient safety as a crucial criterion for assessing imaging modalities.
Purpose of the Study:
- To outline a new imaging paradigm prioritizing diagnostic accuracy and patient safety.
- To establish guidelines for selecting body magnetic resonance imaging (MRI) over computed tomography (CT).
- To consider specific clinical scenarios where MRI offers advantages.
Main Methods:
- Comparative analysis of diagnostic accuracy between CT and MRI.
- Evaluation of imaging modality strengths, including CT's spatial resolution and MRI's soft tissue contrast.
- Integration of patient safety, particularly radiation exposure, into the decision-making process.
Main Results:
- CT excels in scenarios requiring high spatial resolution for detecting subtle abnormalities like lung nodules or renal calculi.
- MRI demonstrates superior intrinsic soft tissue contrast resolution and sensitivity to intravenous contrast, ideal for intra-organ lesions like liver lesions.
- MRI is indicated when diagnostic accuracy is comparable to CT, especially in radiation-sensitive populations (e.g., pediatric patients) or for serial examinations.
Conclusions:
- The optimal imaging approach balances diagnostic accuracy, patient safety, and cost.
- Patient safety, particularly radiation risk, should be a primary consideration in imaging modality selection.
- MRI is a valuable alternative to CT in specific clinical contexts, enhancing patient care and safety.
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