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Updated: Jul 4, 2026
Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Prognostic role of osteopontin expression in malignant pleural mesothelioma
Susanna Cappia1, Luisella Righi, Dario Mirabelli
1Department of Clinical and Biological Sciences, University of Torino at St Luigi Hospital, Torino, Italy.
Abstract:
Malignant pleural mesothelioma (MPM) represents highly aggressive neoplasms with a mean survival of approximately 10 months. Osteopontin, a glycoprotein involved in cell-matrix interactions correlated with invasion and metastatic spread in several tumors, has recently been proposed as a serum marker of MPM in asbestos-exposed subjects. The aim of this study was to define the prognostic role of osteopontin in MPM. For the study, 32 long-term survivors (>24 months) and a random sample of 69 short-term survivors (
