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Updated: Jul 4, 2026

Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants
Published on: May 14, 2020
[Particle release in metal-on-metal bearings. A risk analysis]
C Heisel1, M Thomsen, E Jakubowitz
1Labor für Biomechanik und Implantatforschung, Orthopädische Universitätsklinik, Heidelberg. Christian.Heisel@ok.uni-heidelberg.de
Abstract:
Modern metal-on-metal bearings show very low wear rates but release particles and ions from the articulating surfaces into the joint and the whole organism. Especially during the run-in period an increased number of particles is produced. The released metal ions potentially trigger cytotoxic, cancerogenic and allergic reactions, which can impair the patient's health locally or systemically. Many surgeons fear a hypersensitivity reaction to the metal ions of the CoCr alloy in their patients. Today it is assumed that the incidence of these implant-related complications is very low but in some cases it will lead to early failure of the implant. Because the available alternative bearing combinations (ceramic-on-polyethylene and ceramic-on-ceramic) also bear the risk of severe complications, a final statement on the best and safest bearing choice for the patient cannot be made based on the currently existing data.
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