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Published on: June 11, 2012
Insulin pump therapy in children and adolescents with type 1 diabetes: the Italian viewpoint
Leonardo Pinelli1, Ivana Rabbone, Silvana Salardi
1Childhood Diabetes Unit, University of Verona, Italy. l.pinelli@univr.it
Insights
Italian experts adapted international insulin pump therapy guidelines for children with type 1 diabetes, considering local factors and legal requirements for safe and effective treatment.
Area of Science:
- Pediatric Endocrinology
- Diabetes Management
- Medical Guidelines
Background:
- International recommendations for insulin pump therapy in pediatric type 1 diabetes were reviewed.
- Adaptation of guidelines for the Italian context was necessary.
Purpose of the Study:
- To translate and adapt international insulin pump therapy recommendations for Italian children and adolescents with type 1 diabetes.
- To ensure guidelines are contextually relevant and legally compliant.
Main Methods:
- Literature review and evidence-based recommendations.
- Evaluation of patient selection, therapy planning, device choice, and follow-up.
- Cost-effectiveness analysis of insulin pump therapy versus multiple daily injections.
Main Results:
- Adaptations were made for Italian diet, lifestyle, and legal framework.
- Specific considerations for neonatal diabetes and an "informed therapeutic agreement" were introduced.
- Guidelines address various scenarios including sick days, travel, and exercise.
Conclusions:
- Clinical guidelines require faithful adaptation to local languages and contexts.
- International collaboration in developing localized guidelines is crucial for effective diabetes management.
- Adherence to specific national legal and cultural particularities enhances guideline utility.
Background And Aim:
A panel of experts of the Italian Society of Paediatric Endocrinology and Diabetology translated into Italian the international insulin pump therapy recommendations in children and adolescents with type 1 diabetes.
Methods:
After an extensive review of the literature using evidence-based recommendations, several issues were taken into account, such as patient selection, advantages and disadvantages, instrument choice, insulin type, therapy planning and follow-up, emergencies, nutrition, particular occasions (like parties, holidays, sick days, travels), exercise, continuous glucose monitoring and integrated system, neonatal diabetes. The panel evaluated the cost-effectiveness of insulin pump therapy compared to multiple daily injection therapy, analysing the cost-benefit ratio.
Results:
Some tweak was needed due to the Italian dietetic singularity, meal schedule, climate and lifestyle. Insulin pump therapy in neonatal diabetes is a new issue and no guidelines have been published yet for this age-group. Moreover, legal issues according to the Italian law have been added and are peculiarity of our recommendations. An "informed therapeutic agreement" between the patient and his/her family and the diabetic team has to be signed before starting insulin pump therapy.
Conclusions:
We think that nowadays the need for clinical guidelines is important and worth the effort that all countries develop faithful adaptation into their local languages taking into account specific contexts and local peculiarities, without making substantial modifications to the original text.
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