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Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
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What do perceived cognitive problems reflect?

Catherine M Bender1, Maria L Pacella, Susan M Sereika

  • 1University of Pittsburgh School of Nursing, 3500 Victoria Street, Suite 415, Pittsburgh, PA 15261, USA. cbe100@pitt.edu

The Journal of Supportive Oncology
|June 17, 2008
PubMed
Summary
This summary is machine-generated.

Breast cancer survivors often report cognitive issues. This study found that perceived cognitive problems in women undergoing hormonal therapy correlate with objective cognitive impairments, especially in learning and memory.

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Area of Science:

  • Oncology
  • Neuroscience
  • Psychology

Background:

  • Cognitive dysfunction is a common complaint among women with breast cancer during and after adjuvant therapy.
  • Patient perceptions of cognitive difficulties are expected to align with objectively measured cognitive impairments.

Purpose of the Study:

  • To investigate the relationship between perceived cognitive function and objectively measured cognitive abilities in early-stage breast cancer patients receiving hormonal therapy.
  • To specifically examine objective measures of learning and memory as primary endpoints.

Main Methods:

  • Exploratory study design.
  • Included a comprehensive battery of objective cognitive function tests.
  • Focused on early-stage breast cancer patients undergoing hormonal therapy.

Main Results:

  • Results indicated a relationship between women's self-reported cognitive problems and objectively measured cognitive impairments.
  • Specific attention was given to learning and memory domains.
  • Explored correlations between perceived issues and impairments across various cognitive domains.

Conclusions:

  • Women's reported cognitive problems warrant further assessment to understand underlying causes.
  • Findings suggest the need for appropriate interventions for cognitive difficulties in breast cancer patients.
  • Highlights the importance of validating patient-reported outcomes with objective cognitive measures.