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Updated: Jul 4, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Extensive benign sinonasal squamous papilloma.

I P Tang¹, N Prepageran

¹Department of Otorhinolaryngology, Faculty of Medicine, University of Malaya, 50630 Kuala Lumpur. ingptang@yahoo.com

The Medical Journal of Malaysia

|June 17, 2008

Summary

This summary is machine-generated.

A rare, extensive benign sinonasal squamous papilloma invading sinuses and brain was completely removed. The patient remained disease-free a year after combined endoscopic and transcranial surgery.

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Published on: February 28, 2019

Area of Science:

Otolaryngology
Neurosurgery
Pathology

Background:

Benign sinonasal squamous papillomas are uncommon tumors.
Extensive sinonasal tumors with intracranial extension are exceptionally rare.

Observation:

A patient presented with a large benign sinonasal squamous papilloma.
The tumor involved the right nasal cavity, sphenoid, ethmoid, and maxillary sinuses, with intracranial extension.

Findings:

Complete tumor excision was achieved using a combined endoscopic transnasal and transcranial surgical approach.
The patient experienced no recurrence at one year of follow-up.

Implications:

This case highlights the feasibility of combined endoscopic and open surgical techniques for extensive sinonasal tumors.
Successful management of such rare tumors can lead to favorable long-term outcomes.