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Updated: Jul 4, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
[Otoneurological aspects of the early forms of sclerosis multiplex (SM)]
Ireneusz Rzewnicki1, Elzbieta Pyd, Wiesław Drozdowski
1Klinika Otolaryngologii AM w Białymstoku.
Abstract:
Sclerosis multiplex (SM) is characterized by multifocality of neurological changes and polyphasic course. The disease is caused by indefinite factors in the circumstances of genetically determined immune disorders. The aim of study. An attempt was made to identify otoneurological symptoms accompanying the early stage of sclerosis multiplex (SM). Material and research methods. 103 patients (diagnosed with uncharacteristic otoneurological symptoms, in further clinical observation defined as SM prodromes) were retrospectively examined. The following factors were taken into consideration: character and intensity of dizziness, results of static and dynamic tests, electronystagmography (ENG), caloric test, eye tracking and optokinetic nystagmus. Conclusion. Disorders of: vestibulospinal reflexes, eye tracking, optokinesis, time and regularity of caloric nystagmus occur in the very early stages of SM.
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