Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dialysis01:15

Dialysis

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...
Composition of Body Fluids01:29

Composition of Body Fluids

Water functions as a solvent accommodating various solutes, which can be categorized under electrolytes and non-electrolytes. Non-electrolytes are usually held together by covalent bonds, restricting them from dissociating in solution, thereby leading to a lack of electrically charged components upon dissolving in water. They are predominantly organic molecules, such as glucose, creatinine, and urea. Electrolytes, on the other hand, are compounds that can break down into ions in water.
Peritoneal Dialysis I: Introduction and Procedure01:30

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanisms of Crystalloid versus Colloid Osmosis across the Peritoneal Membrane.

Journal of the American Society of Nephrology : JASN·2018
Same author

Clinically Oriented Patient Maintenance Protocol: A Clinical Consensus of Experts.

The International journal of periodontics & restorative dentistry·2018
Same author

Optimizing Automated Peritoneal Dialysis Using an Extended 3-Pore Model.

Kidney international reports·2017
Same author

Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability.

American journal of physiology. Renal physiology·2017
Same author

A distributed solute model: an extended two-pore model with application to the glomerular sieving of Ficoll.

American journal of physiology. Renal physiology·2017
Same author

Microproteinuria Predicts Organ Failure in Patients Presenting with Acute Pancreatitis.

Digestive diseases and sciences·2016

Related Experiment Video

Updated: Jul 4, 2026

Exploring Arterial Smooth Muscle Kv7 Potassium Channel Function using Patch Clamp Electrophysiology and Pressure Myography
11:02

Exploring Arterial Smooth Muscle Kv7 Potassium Channel Function using Patch Clamp Electrophysiology and Pressure Myography

Published on: September 14, 2012

Optimum electrolyte composition of a dialysis solution.

Bengt Rippe1, Daniele Venturoli

  • 1Department of Nephrology, Lund University, University Hospital of Lund, Lund, Sweden. Bengt.Rippe@med.lu.se

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|September 20, 2008
PubMed
Summary

Optimizing peritoneal dialysis (PD) solutions is key for end-stage renal failure patients. Low-sodium (LNa) solutions show promise for managing fluid overload and blood pressure, but require further study.

Related Experiment Videos

Last Updated: Jul 4, 2026

Exploring Arterial Smooth Muscle Kv7 Potassium Channel Function using Patch Clamp Electrophysiology and Pressure Myography
11:02

Exploring Arterial Smooth Muscle Kv7 Potassium Channel Function using Patch Clamp Electrophysiology and Pressure Myography

Published on: September 14, 2012

Area of Science:

  • Nephrology
  • Biochemistry
  • Medical Technology

Background:

  • Peritoneal dialysis (PD) is a treatment for end-stage renal failure.
  • Conventional PD solutions (CPDSs) have limitations in electrolyte removal, especially in ultrafiltration failure (UFF).
  • Maintaining electrolyte balance and fluid status is crucial for patient homeostasis.

Purpose of the Study:

  • To evaluate the electrolyte composition of PD solutions for optimal patient homeostasis.
  • To explore the efficacy of low-sodium (LNa) PD solutions in managing fluid overload and blood pressure.

Main Methods:

  • Comparison of transperitoneal electrolyte removal by CPDSs versus normal kidney function.
  • Analysis of electrolyte concentrations in CPDSs and their impact on removal rates.
  • Investigation of LNa solutions with glucose compensation in a recent study.

Main Results:

  • CPDSs remove electrolytes inefficiently, with removal largely dependent on ultrafiltration (UF).
  • UFF can lead to electrolyte imbalances, necessitating alternative strategies.
  • A recent study demonstrated promising effects of a daily LNa exchange on blood pressure and fluid status.

Conclusions:

  • PD solution electrolyte composition must be optimized for patient homeostatic needs.
  • LNa solutions offer a potential alternative to dietary salt restriction for managing fluid overload.
  • Large-scale randomized controlled trials are needed to confirm the role of LNa in volume-overloaded PD patients.