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Encapsulating peritoneal sclerosis in Japan.

Yukio Maruyama1, Masaaki Nakayama

  • 1Division of Kidney and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|September 20, 2008
PubMed
Summary

Encapsulating peritoneal sclerosis (EPS) is a severe complication of peritoneal dialysis (PD). This paper reviews EPS clinical stages, incidence in Japan, development mechanisms, and prevention strategies for PD patients.

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Area of Science:

  • Nephrology
  • Gastroenterology
  • Surgical Complications

Background:

  • Encapsulating peritoneal sclerosis (EPS) is a serious complication of peritoneal dialysis (PD).
  • EPS was recognized shortly after PD introduction, with Japan reporting increasing cases within a decade.
  • The pathophysiology of EPS remains incompletely understood.

Purpose of the Study:

  • To discuss the clinical stages of EPS.
  • To review the incidence of EPS in Japan.
  • To explore EPS development mechanisms, management, and prevention strategies.

Main Methods:

  • Literature review and synthesis of existing data on EPS.
  • Analysis of clinical presentations and diagnostic criteria for EPS.
  • Examination of epidemiological data from Japan regarding EPS incidence.

Main Results:

  • EPS presents with distinct clinical stages.
  • Japan has observed a significant rise in EPS cases post-PD introduction.
  • Current understanding of EPS development mechanisms is limited.

Conclusions:

  • Early recognition and understanding of EPS are crucial for PD patients.
  • Further research into EPS pathophysiology is needed for effective prevention and management.
  • Comprehensive strategies are required to address EPS complications in PD.