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What is the normal intra-abdominal pressure in critically ill children and how should we measure it?
J Chiaka Ejike1, Khaled Bahjri, Mudit Mathur
1Department of Pediatrics, Division of Pediatric Critical Care, Loma Linda University, School of Medicine, Loma Linda, California, USA. jejike@ahs.llumc.edu
Insights
The minimum optimal volume for accurate intra-abdominal pressure (IAP) measurement in children using the intravesical method is 3 mL. This study found the normal IAP in critically ill children to be 7 ± 3 mm Hg.
Area of Science:
- Pediatric critical care medicine
- Physiology
- Medical instrumentation
Background:
- The intravesical method is the gold standard for indirect intra-abdominal pressure (IAP) measurement.
- Standard instillation volumes used in adults may not be accurate for pediatric patients.
- Optimal instillation volumes for pediatric IAP measurement require further investigation.
Purpose of the Study:
- Determine normal intra-abdominal pressure (IAP) in critically ill children.
- Identify the optimal instillation volume for accurate IAP measurement using the intravesical method in children.
Main Methods:
- Prospective observational study conducted in a tertiary pediatric intensive care unit.
- Ninety-six mechanically ventilated children under 18 years old without intra-abdominal hypertension were enrolled.
- Graduated instillation volumes (3-50 mL) of normal saline were used via urethral catheter to measure IAP with the AbViser device.
Main Results:
- Normal intra-abdominal pressure (IAP) in critically ill children was 7 ± 3 mm Hg, consistent across weight groups.
- The minimum optimal instillation volume for accurate IAP measurement was consistently 3 mL, regardless of patient weight.
- Mean optimal volumes varied between weight strata, highlighting the importance of a standardized minimum volume.
Conclusions:
- The mean intra-abdominal pressure (IAP) in critically ill children is 7 ± 3 mm Hg.
- A minimum instillation volume of 3 mL is recommended for accurate pediatric IAP measurement via the intravesical method.
- Intra-abdominal pressure (IAP) exceeding 10 mm Hg should be considered elevated in children.
Introduction:
The intravesical method has been validated and is considered the gold standard for indirect intra-abdominal pressure (IAP) measurements. In adults, a standard volume (25 mL) is instilled into the bladder to measure IAP. However, the optimal volume for accurate IAP measurements in children has not been well studied and using inappropriate volumes could give erroneous IAP readings.
Objective:
To determine the normal IAP in critically ill children and the optimal volume for IAP measurement by the intravesical method in this population.
Design:
Prospective observational study.
Setting:
Tertiary pediatric intensive care unit.
Patients:
Ninety-six mechanically ventilated children younger than 18 yrs of age with no clinical evidence of intra-abdominal hypertension.
Measurements And Results:
Graduated volumes of normal saline in increments of 3-50 mL were instilled in the bladder via a urethral catheter. IAP was recorded by using the AbViser device (WolfeTory Medical, Inc., Salt Lake City, UT) with each instillation. A pressure-volume curve was generated for every patient, and the minimum and mean optimal volumes were determined from this curve. Data were analyzed by stratification of patients according to weights 0-10 kg, >10-20 kg, and >20-50 kg. Descriptive statistics was used for statistical analysis. Normal IAP for critically ill children was 7 +/- 3 and was similar in the different weight groups (p = .745). Although the mean optimal volume to measure accurate IAP was variable in the different weight groups, the minimum optimal volume was 3 mL irrespective of weight.
Conclusions:
Mean IAP in critically ill children is 7 +/- 3 mm Hg. The minimum optimal volume needed to accurately measure IAP by the intravesical method in children is 3 mL. We recommend that 3 mL be the standard instillation volume for IAP measurement by the intravesical method in children. IAP >10 mm Hg should be considered elevated in children.
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