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Related Concept Videos

Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Stress and Mental Health01:30

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
Diagnostic and Statistical Manual of Mental Disorders (DSM)01:27

Diagnostic and Statistical Manual of Mental Disorders (DSM)

The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
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CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...

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Related Experiment Video

Updated: Jul 4, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

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Published on: June 23, 2023

Mood disorders and substance use disorder: a complex comorbidity.

Susan B Quello1, Kathleen T Brady, Susan C Sonne

  • 1Medical University of South Carolina, Charleston, SC 29425, USA.

Science & Practice Perspectives
|June 17, 2008
PubMed
Summary

Treating mood disorders alongside substance use disorders improves outcomes. Early screening and tailored treatments, including psychotherapy and specific medications, are key for patients with co-occurring conditions.

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Area of Science:

  • Psychiatry
  • Addiction Medicine

Background:

  • Mood disorders are common in substance use disorder (SUD) patients.
  • Co-occurring mood disorders complicate SUD treatment and outcomes.

Purpose of the Study:

  • To highlight the importance of treating mood disorders in SUD patients.
  • To outline effective screening and treatment strategies for co-occurring conditions.

Main Methods:

  • Methodical, staged screening and assessment.
  • Prioritizing psychotherapeutic interventions.
  • Selecting medications proven effective for co-occurring SUD.

Main Results:

  • Effective treatment of mood disorders can reduce substance craving and use.
  • Improved patient outcomes are associated with integrated care.

Conclusions:

  • Integrated treatment for co-occurring mood and substance use disorders is essential.
  • Collaboration between mental health and substance abuse providers is crucial for patient success.