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Glial cytoplasmic inclusions in neurologically normal elderly: prodromal multiple system atrophy?

Hiroshige Fujishiro1, Tae-Beom Ahn, Roberta Frigerio

  • 1Department of Pathology (Neuropathology), Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

Acta Neuropathologica
|June 17, 2008
PubMed
Summary

This study found alpha-synuclein pathology, including glial cytoplasmic inclusions (GCI) resembling preclinical multiple system atrophy (MSA), in a small percentage of neurologically normal elderly individuals. Further research is needed to understand if this represents early MSA or a benign age-related condition.

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