The gene for human growth hormone-releasing factor (GHRF) maps to or near chromosome 20p12
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V V Rao1, C Löffler, S Schnittger
1Institut für Humangenetik, Universität Göttingen, Germany.
Cytogenetics and Cell Genetics
|January 1, 1991
Abstract:
Growth hormone-releasing factor (GHRF), a hypothalamic releasing factor also named somatocrinin, influences the secretion and synthesis of growth hormone. Human GHRF is encoded by a single gene which was assigned to chromosome 20 by dot-blot analysis of DNA from dual laser sorted chromosomes. Using a radioactive cDNA probe, we localized the GHRF gene to chromosome 20p12 or near band 20p12.