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Updated: Jul 4, 2026
Operation of Laboratory Photobioreactors with Online Growth Measurements and Customizable Light Regimes
Published on: October 28, 2021
Determination of reactor biomass by acoustic resonance densitometry
B C Blake-Coleman1, D J Clarke, M R Calder
1Biosensor Group, Microbial Technology Laboratory, Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, England SP4 OJG.
Abstract:
Acoustic resonance densitometry (ARD) is reported as a method suitable not only for precise investigations into changes of specific gravity in bioreactor media but also as a technique able to provide an accurate wide range and direct determination of cellular mass in fermentation processes. It is further shown that this method can replace present optical procedures, minimizing dilution errors and operator involvement and is suitable for development as an on-line biomass monitoring system.
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