Related Experiment Videos
Risk factors for breast cancer: a hospital-based case-control study
B Kocic1, B Petrovic, S Filipovic
1Faculty of Medicine, Institute of Epidemiology, University of Nis, Bul.dr Z. Djindjića 50, Nis, Serbia. biljaizzz@yahoo.com
Purpose:
The factors responsible for the genesis of breast cancer remain unclear. A case-control study was undertaken to investigate the possibility of an association between hypothesized risk factors and the development of breast cancer in Serbia.
Patients And Methods:
This hospital-based case-control study comprised 120 new breast cancer cases and 120 hospital controls matched with respect to age (+/- 2 years). This study used a targeted and detailed questionnaire to obtain information from respondents. Odds ratios (OR) and 95% confidence intervals (95% CI) were calculated from multivariate conditional logistic regression models.
Results:
Five independent predictors of breast cancer were: delayed age at first birth (OR=6.1, 95% CI=4.2-12.4), alcohol consumption (OR=4.8, 95% CI=1.9-12.4), family history of breast cancer in 2nd degree relatives (OR=2.5, 95% CI=1.4-4.3), never having breastfed (OR=5.2, 95% CI=1.4-18.5) and maternal death in childhood (OR=3.3, 95% CI=1.2-8.6).
Conclusion:
The results of this study confirmed that the aetiology of breast cancer in Serbia, as elsewhere, is complex. More research is needed to understand the interactions between factors that could affect vulnerability to breast cancer.
Related Concept Videos
Cancer Prevention
Some...
Cancer Survival Analysis
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Hazard Ratio
For example, in a clinical trial evaluating a...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...